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KMID : 0861119990030020079
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Korean Journal of Oriental Preventive Medicine
1999 Volume.3 No. 2 p.79 ~ p.89
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Effects of the Water Extract of Houttuynia cordata on the Accumulation of Cadmium in Organ of Rat (I)
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Lee Jeong-Ho
Kang Kil-Ung
Jeung J.Y.
Han J.M.
Lee Ki-Nam
Jung Woo-Young
Han Du-Seok
You Il-Soo
Kim Jong-Soo
Baek Seung-Hwa
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Abstract
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This study was conducted to investigate the antitoxic component in aqueous extract of Houttuynia cordata . The results were as follows: Generally, detoxication effects by Houttuynia cordata extract increased in proportion to the extract concentrations. When 40mg/kg dosage of Houttuynia cordata extract was administered, it showed the highest antitoxic effects in metallothionein induction. After the extract treatment, body weights increased in proportion to the extract concentration. However, after 3 weeks, the body weight decreased insignificantly. From the above results, Houttuynia cordata extract increased metallothionein concentration and decreased the toxicity of cadmium in rats.
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KEYWORD
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Houttuynia cordata THUNB, Antitoxic effects, Metallothionein
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